Nanocoatings in the medical industry

Published March 9 2021, 233 pages, 50 tables, 64 figures

In medical and healthcare facilities it is necessary to equip materials and surfaces with a high level of hygiene using antimicrobial agents to protect them against bacteria and other micro organisms to prevent infections caused by bacteria and contribute significantly to reduce health costs. Challenges in medical device coatings include:

biocompatibility;
coating adhesion;
uniform coverage over challenging shapes;
strength;
durability.

Benefits of nanoscale coatings in this sector include long lasting antimicrobial effect, constant release of the active substance, effectiveness against bacteria and other micro-organisms, no chemical impurities, easy processing, no changes to the characteristics of the equipped material, and no later discolouration of the equipped material. Nanocoatings are already finding application in life sciences & healthcare in enabling anti-bacterial surfaces for medical catheters, added to paints and lacquers used to coat operating tables, door knobs and door handles in hospitals and as ultra-hard porous coatings for surgical and orthopedic implants like screws, plates or joint implants.

The medical market will be a high growth area for nanoscale coatings over the next 5-10 years, and this is reflected in the high number of companies exploiting technology in this area, especially in the anti-microbial domain. The main market driver in this area is the prevention of the spread of deadly infections in medical facilities. Drug-resistant bacteria, the so-called "superbugs," are a growing problem in hospitals worldwide and poor hygiene among staff is often blamed for the spread of such infections.

Report contents include:

Advantages of nanocoatings in the medical and healthcare industry.
Types of nanocoatings.
Anti-viral and anti-microbial nanocoatings industry analysis.
Types of nanomaterials utilized in medical nanocoatings.
Profiles of 107 companies.

Table of contents (.pdf)

1 EXECUTIVE SUMMARY 18

1.1 Why nanocoatings? 18
1.2 Advantages over traditional coatings 18
1.3 Improvements and disruption in coatings markets 20
1.4 Anti-viral nanoparticles and nanocoatings 22
- 1.4.1.1 Reusable Personal Protective Equipment (PPE) 24
- 1.4.1.2 Wipe on coatings 24
- 1.4.1.3 Facemask coatings 24
- 1.4.1.4 Long-term mitigation of surface contamination with nanocoatings 25
1.5 End user market for nanocoatings 26
1.6 The nanocoatings market in 2020 29
1.7 Global market size, historical and estimated to 2020 29
- 1.7.1 Global revenues for nanocoatings 2010-2030 29
- 1.7.2 Regional demand for nanocoatings 30
1.8 Market challenges 31
1.9 Toxicity and environmental considerations 32
1.10 Impact of COVID-19 on the market 33
1.11 Market outlook in 2021 33

2 NANOCOATINGS TECHNICAL ANALYSIS 35

2.1 Properties of nanocoatings 35
2.2 Benefits of using nanocoatings 36
- 2.2.1 Types of nanocoatings 37
2.3 Production and synthesis methods 37

3 NANOMATERIALS IN MEDICAL NANOCOATINGS 50

3.1 Metallic-based coatings 50
3.2 Polymer-based coatings 51
3.3 Graphene 53
- 3.3.1 Properties 53
- 3.3.2 Graphene oxide 55
  - 3.3.2.1 Anti-bacterial activity 55
  - 3.3.2.2 Anti-viral activity 56
- 3.3.3 Reduced graphene oxide (rGO) 56
- 3.3.4 Application in medical and healthcare 57
  - 3.3.4.1 Anti-microbial wound dressings 57
  - 3.3.4.2 Medical textiles 58
  - 3.3.4.3 Anti-microbial medical devices and implants 58
3.4 Silicon dioxide/silica nanoparticles (Nano-SiO2) 59
- 3.4.1 Properties 59
- 3.4.2 Application in medical and healthcare 60
  - 3.4.2.1 Antimicrobial and antiviral activity 60
  - 3.4.2.2 Easy-clean and dirt repellent coatings 60
3.5 Silver nanoparticles (Ag-NPs) 61
- 3.5.1 Properties 61
- 3.5.2 Application in medical nanocoatings 61
  - 3.5.2.1 Textiles 63
  - 3.5.2.2 Wound dressings 63
  - 3.5.2.3 Air filtration 63
- 3.5.3 Companies 63
3.6 Titanium Dioxide nanoparticles (TiO2-NPs) 65
- 3.6.1 Properties 65
  - 3.6.1.1 Exterior and construction glass coatings 67
  - 3.6.1.2 Outdoor air pollution 68
  - 3.6.1.3 Interior coatings 69
  - 3.6.1.4 Improving indoor air quality 69
  - 3.6.1.5 Medical facilities 70
- 3.6.2 Application in medical nanocoatings 70
  - 3.6.2.1 Antimicrobial coating indoor light activation 70
3.7 Nano-Zinc oxide (nano-ZnO/ ZnO-NPs) 71
- 3.7.1 Properties 71
- 3.7.2 Application in medical nanocoatings 72
  - 3.7.2.1 Sterilization dressings 72
  - 3.7.2.2 Anti-bacterial surfaces in construction and building ceramics and glass 73
  - 3.7.2.3 Antimicrobial packaging 73
  - 3.7.2.4 Anti-bacterial textiles 73
3.8 Nanocellulose 75
- 3.8.1 Properties 75
- 3.8.2 Application in medical nanocoatings 76
  - 3.8.2.1 Cellulose nanofibers 76
  - 3.8.2.2 Cellulose nanocrystals (CNC) 76
3.9 Carbon nanotubes 76
- 3.9.1 Properties 76
- 3.9.2 Application in medical nanocoatings 76
3.10 Fullerenes 77
- 3.10.1 Properties 77
- 3.10.2 Application in medical nanocoatings 78
3.11 Copper nanoparticles (Cu-NPs) 78
- 3.11.1 Properties 78
- 3.11.2 Application in medical nanocoatings 79
- 3.11.3 Companies 79
3.12 Gold nanoparticles (Au-NPs) 80
- 3.12.1 Properties 80
- 3.12.2 Application in medical nanocoatings 80
3.13 Chitosan nanoparticles 80
- 3.13.1 Properties 80
- 3.13.2 Application in medical nanocoatings 82
  - 3.13.2.1 Wound dressings 82
3.14 Hydrophobic and Hydrophilic coatings and surfaces 83
- 3.14.1 Hydrophilic coatings 83
- 3.14.2 Hydrophobic coatings 83
  - 3.14.2.1 Properties 84
  - 3.14.2.2 Application in facemasks 85
3.15 Superhydrophobic coatings and surfaces 85
- 3.15.1 Properties 85
  - 3.15.1.1 Anti-microbial use 86
  - 3.15.1.2 Durability issues 87
  - 3.15.1.3 Nanocellulose 87
3.16 Oleophobic and omniphobic coatings and surfaces 88
- 3.16.1 SLIPS 88
- 3.16.2 Covalent bonding 89
- 3.16.3 Step-growth graft polymerization 89
- 3.16.4 Applications 89

4 MARKET SEGMENT ANALYSIS, MEDICAL COATINGS MARKET 91

4.1 ANTI-MICROBIAL, ANTI-VIRAL AND ANTI-FUNGAL NANOCOATINGS 91
- 4.1.1 Market drivers and trends 93
- 4.1.2 Applications 98
- 4.1.3 Global revenues 2010-2030 99
- 4.1.4 Companies 103
4.2 ANTI-FOULING AND EASY-TO-CLEAN NANOCOATINGS 106
- 4.2.1 Market drivers and trends 107
- 4.2.2 Benefits of anti-fouling and easy-to-clean nanocoatings 108
- 4.2.3 Applications 108
- 4.2.4 Global revenues 2010-2030 108
- 4.2.5 Companies 112
4.3 SELF-CLEANING (BIONIC) NANOCOATINGS 115
- 4.3.1 Market drivers and trends 116
- 4.3.2 Benefits of self-cleaning nanocoatings 116
- 4.3.3 Global revenues 2010-2030 117
- 4.3.4 Companies 121
4.4 SELF-CLEANING (PHOTOCATALYTIC) NANOCOATINGS 123
- 4.4.1 Market drivers and trends 124
- 4.4.2 Benefits of photocatalytic self-cleaning nanocoatings 124
- 4.4.3 Applications 125
  - 4.4.3.1 Self-Cleaning Coatings 125
  - 4.4.3.2 Indoor Air Pollution and Sick Building Syndrome 125
  - 4.4.3.3 Outdoor Air Pollution 125
  - 4.4.3.4 Water Treatment 126
- 4.4.4 Global revenues 2010-2030 126
- 4.4.5 Companies 131
4.5 ANTI-FOGGING COATINGS 134
- 4.5.1 Applications 134

5 COMPANY PROFILES 135 (107 company profiles)

6 RESEARCH METHODOLOGY 220

6.1 Aims and objectives of the study 220
6.2 Market definition 221
- 6.2.1 Properties of nanomaterials 221
6.2.2 Categorization 222

7 REFERENCES 224

TABLES

Table 1. Properties of nanocoatings. 19
Table 2. Market drivers and trends in nanocoatings. 20
Table 3: End user markets for nanocoatings. 26
Table 4: Global revenues for nanocoatings, 2010-2030, millions USD. 29
Table 5: Market and technical challenges for nanocoatings. 31
Table 6. Toxicity and environmental considerations for anti-viral coatings. 32
Table 7: Technology for synthesizing nanocoatings agents. 37
Table 8: Film coatings techniques. 38
Table 9: Nanomaterials used in nanocoatings and applications. 51
Table 10: Graphene properties relevant to application in coatings. 54
Table 11. Bactericidal characters of graphene-based materials. 56
Table 12. Markets and applications for nanocoatings in medical and healthcare. 57
Table 13. Commercial activity in antimicrobial and antiviral nanocoatings graphene nanocoatings. 58
Table 14. Markets and applications for antimicrobial nanosilver nanocoatings. 62
Table 15. Companies developing antimicrobial silver nanocoatings. 64
Table 16. Antibacterial effects of ZnO NPs in different bacterial species. 73
Table 17. Types of carbon-based nanoparticles as antimicrobial agent, their mechanisms of action and characteristics. 78
Table 18. Companies developing antimicrobial copper nanocoatings. 79
Table 19. Mechanism of chitosan antimicrobial action. 81
Table 20: Contact angles of hydrophilic, super hydrophilic, hydrophobic and superhydrophobic surfaces. 84
Table 21: Disadvantages of commonly utilized superhydrophobic coating methods. 87
Table 22: Applications of oleophobic & omniphobic coatings. 89
Table 23: Anti-microbial, anti-viral and anti-fungal nanocoatings-Nanomaterials used, principles, properties and applications 92
Table 24. Nanomaterials utilized in antimicrobial and antiviral nanocoatings coatings-benefits and applications. 97
Table 25: Antimicrobial and antiviral nanocoatings markets and applications. 99
Table 26: Market assessment of antimicrobial and antiviral nanocoatings. 100
Table 27: Opportunity for antimicrobial and antiviral nanocoatings. 100
Table 28: Revenues for antimicrobial and antiviral nanocoatings, 2010-2030, US$. 101
Table 29: Antimicrobial and antiviral nanocoatings product and application developers. 103
Table 30: Anti-fouling and easy-to-clean nanocoatings-Nanomaterials used, principles, properties and applications. 106
Table 31: Market drivers and trends in Anti-fouling and easy-to-clean nanocoatings. 107
Table 32: Anti-fouling and easy-to-clean nanocoatings markets, applications and potential addressable market. 109
Table 33: Market assessment for anti-fouling and easy-to-clean nanocoatings. 109
Table 34: Revenues for anti-fouling and easy-to-clean nanocoatings, 2010-2030, US$. 110
Table 35: Anti-fouling and easy-to-clean nanocoatings product and application developers. 112
Table 36: Self-cleaning (bionic) nanocoatings-Nanomaterials used, principles, properties and applications. 115
Table 37: Market drivers and trends in Self-cleaning (bionic) nanocoatings. 116
Table 38: Self-cleaning (bionic) nanocoatings-Markets and applications. 118
Table 39: Market assessment for self-cleaning (bionic) nanocoatings. 118
Table 40: Revenues for self-cleaning nanocoatings, 2010-2030, US$. 119
Table 41: Self-cleaning (bionic) nanocoatings product and application developers. 121
Table 42: Self-cleaning (photocatalytic) nanocoatings-Nanomaterials used, principles, properties and applications. 123
Table 43: Market drivers and trends in photocatalytic nanocoatings. 124
Table 44: Photocatalytic nanocoatings-Markets, applications and potential addressable market size by 2027. 127
Table 45: Market assessment for self-cleaning (photocatalytic) nanocoatings. 128
Table 46: Revenues for self-cleaning (photocatalytic) nanocoatings, 2010-2030, US$. 128
Table 47: Self-cleaning (photocatalytic) nanocoatings product and application developers. 131
Table 48. Market overview of anti-fog coatings in healthcare and medical. 134
Table 49. Photocatalytic coating schematic. 156
Table 50: Categorization of nanomaterials. 222

FIGURES

Figure 1. Schematic of anti-viral coating using nano-actives for inactivation of any adhered virus on the surfaces. 23
Figure 2. Face masks coated with antibacterial & antiviral nanocoating. 25
Figure 3: Global revenues for nanocoatings, 2010-2030, millions USD. 30
Figure 4: Regional demand for nanocoatings, 2019, millions USD. 31
Figure 5: Hydrophobic fluoropolymer nanocoatings on electronic circuit boards. 36
Figure 6: Nanocoatings synthesis techniques. 38
Figure 7: Techniques for constructing superhydrophobic coatings on substrates. 40
Figure 8: Electrospray deposition. 42
Figure 9: CVD technique. 43
Figure 10: Schematic of ALD. 45
Figure 11. A substrate undergoing layer-by-layer (LbL) nanocoating. 46
Figure 12: SEM images of different layers of TiO2 nanoparticles in steel surface. 46
Figure 13: The coating system is applied to the surface. The solvent evaporates. 48
Figure 14: A first organization takes place where the silicon-containing bonding component (blue dots in figure 2) bonds covalently with the surface and cross-links with neighbouring molecules to form a strong three-dimensional. 48
Figure 15: During the curing, the compounds organise themselves in a nanoscale monolayer. The fluorine-containing repellent component (red dots in figure) on top makes the glass hydro- phobic and oleophobic. 48
Figure 16: Graphair membrane coating. 54
Figure 17: Antimicrobial activity of Graphene oxide (GO). 55
Figure 18: Hydrophobic easy-to-clean coating. 60
Figure 19 Anti-bacterial mechanism of silver nanoparticle coating. 61
Figure 20: Mechanism of photocatalysis on a surface treated with TiO2 nanoparticles. 66
Figure 21: Schematic showing the self-cleaning phenomena on superhydrophilic surface. 66
Figure 22: Titanium dioxide-coated glass (left) and ordinary glass (right). 68
Figure 23: Self-Cleaning mechanism utilizing photooxidation. 68
Figure 24: Schematic of photocatalytic air purifying pavement. 69
Figure 25: Schematic of photocatalytic indoor air purification filter. 70
Figure 26. Schematic of antibacterial activity of ZnO NPs. 73
Figure 27: Types of nanocellulose. 75
Figure 28. Mechanism of antimicrobial activity of carbon nanotubes. 77
Figure 29: Fullerene schematic. 77
Figure 30. TEM images of Burkholderia seminalis treated with (a, c) buffer (control) and (b, d) 2.0 mg/mL chitosan; (A: additional layer; B: membrane damage). 81
Figure 31: (a) Water drops on a lotus leaf. 83
Figure 32: A schematic of (a) water droplet on normal hydrophobic surface with contact angle greater than 90° and (b) water droplet on a superhydrophobic surface with a contact angle > 150°. 84
Figure 33: Contact angle on superhydrophobic coated surface. 86
Figure 34: Self-cleaning nanocellulose dishware. 88
Figure 35: SLIPS repellent coatings. 89
Figure 36: Omniphobic coatings. 90
Figure 37: Market drivers and trends in antimicrobial and antiviral nanocoatings. 93
Figure 38. Nano-coated self-cleaning touchscreen. 100
Figure 39: Revenues for antimicrobial and antiviral nanocoatings, 2010-2030, US$. 102
Figure 40. Revenues for antimicrobial and antiviral nanocoatings, 2019-2030, US$, adjusted for COVID-19 related demand, conservative and high estimates. 103
Figure 41: Anti-fouling treatment for heat-exchangers. 108
Figure 42: Markets for anti-fouling and easy clean nanocoatings, by %. 108
Figure 43: Potential addressable market for anti-fouling and easy-to-clean nanocoatings by 2030. 110
Figure 44: Revenues for anti-fouling and easy-to-clean nanocoatings 2010-2030, millions USD. 111
Figure 45. Revenues for anti-fouling and easy-to-clean nanocoatings, 2019-2030, US$, adjusted for COVID-19 related demand, conservative and high estimates 112
Figure 46: Self-cleaning superhydrophobic coating schematic. 117
Figure 48: Potential addressable market for self-cleaning (bionic) nanocoatings by 2030. 119
Figure 49: Revenues for self-cleaning nanocoatings, 2010-2030, US$. 120
Figure 50. Revenues for self-cleaning (bionic) nanocoatings, 2019-2030, US$, adjusted for COVID-19 related demand, conservative and high estimates 121
Figure 51: Principle of superhydrophilicity. 125
Figure 52: Schematic of photocatalytic air purifying pavement. 126
Figure 53: Tokyo Station GranRoof. The titanium dioxide coating ensures long-lasting whiteness. 127
Figure 54: Markets for self-cleaning (photocatalytic) nanocoatings 2019, %. 127
Figure 55: Potential addressable market for self-cleaning (photocatalytic) nanocoatings by 2030. 128
Figure 56: Revenues for self-cleaning (photocatalytic) nanocoatings, 2010-2030, US$. 130
Figure 57. Revenues for self-cleaning (photocatalytic) nanocoatings, 2019-2030, US$, adjusted for COVID-19 related demand, conservative and high estimates 131
Figure 58. Face shield with anti-fog coating. 134
Figure 59. GrapheneCA anti-bacterial and anti-viral coating. 162
Figure 60. Microlyte® Matrix bandage for surgical wounds. 169
Figure 61. Self-cleaning nanocoating applied to face masks. 171
Figure 62. NanoSeptic surfaces. 187
Figure 63. NascNanoTechnology personnel shown applying MEDICOAT to airport luggage carts. 190
Figure 64. Applications of Titanystar. 218

The Global Market for Nanocoatings in the Medical Industry

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<img class="size-full wp-image-6888 alignright" src="https://www.futuremarketsinc.com/wp-content/uploads/2021/03/cover-1.jpeg" alt="" width="199" height="280" />Published March 9 2021, 233 pages, 50 tables, 64 figures

1 EXECUTIVE SUMMARY 18

2 NANOCOATINGS TECHNICAL ANALYSIS 35

3 NANOMATERIALS IN MEDICAL NANOCOATINGS 50

4 MARKET SEGMENT ANALYSIS, MEDICAL COATINGS MARKET 91

5 COMPANY PROFILES 135 (107 company profiles)

6 RESEARCH METHODOLOGY 220

7 REFERENCES 224

TABLES

FIGURES

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Published March 9 2021, 233 pages, 50 tables, 64 figures