Nano-cocoons for anti-cancer drug delivery

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Who: North Carolina State University and the University of North Carolina at Chapel Hil.

What: Bioinspired cocoon-like anticancer drug delivery system consisting of a deoxyribonuclease (DNase)-degradable DNA nanoclew (NCl) embedded with an acid-responsive DNase I nanocapsule (NCa).

Where: Anti-cancer therapy.

When: Preparing to launch preclinical testing.

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Image: Nano-cocoon with ligands on surface that bind to receptors on the surface of cancer cells. (Image Zhen Gu)