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Biomanufacturing Scaling Up Production of Biopharmaceuticals and Biochemicals min
Biomanufacturing Scaling Up Production of Biopharmaceuticals and Biochemicals min

The Global Biomanufacturing Market 2024-2035

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Biopharmaceuticals, Industrial enzymes, Biofuels, Bioplastics, Biochemicals, and Bio-agritech solutions.

  • Published: May 2024
  • Pages: 1,175
  • Tables: 101
  • Figures: 194
  • Series: Bio-Economy 

 

The biomanufacturing market is a rapidly growing sector that involves the production of various products using biological systems, such as living cells, enzymes, or other biological components. The market encompasses a wide range of applications, from biopharmaceuticals and industrial enzymes to biofuels and bio-based chemicals. Biomanufacturing processes often rely on renewable feedstocks and generate less waste compared to traditional chemical manufacturing methods. This makes biomanufacturing a more sustainable and environmentally friendly approach to producing various products. Biological systems can produce complex molecules with high specificity and purity, which is particularly important for the production of biopharmaceuticals and other high-value products. Biomanufacturing enables the production of novel and superior products that may be difficult or impossible to obtain through chemical synthesis.  Biomanufacturing plays a crucial role in addressing global challenges, such as healthcare, energy security, and environmental sustainability. For example, biopharmaceuticals produced through biomanufacturing processes have revolutionized the treatment of various diseases, while biofuels and bio-based chemicals offer alternatives to fossil-based products. Biomanufacturing encompasses several sub-markets, covered in this report including:

  • Biopharmaceuticals: production of drugs and vaccines using living cells or their components. It includes the manufacture of monoclonal antibodies, recombinant proteins, cell and gene therapies, and other biologics.
  • Industrial enzymes: enzymes produced through biomanufacturing processes are used in various industries, such as food and beverage, textiles, detergents, and paper and pulp. These enzymes catalyze specific reactions and improve the efficiency of industrial processes.
  • Biofuels: biomanufacturing technologies are used to produce sustainable fuels, such as bioethanol and biodiesel, from renewable feedstocks like corn, sugarcane, or algae.
  • Bio-based chemicals: production of chemicals, such as platform chemicals, specialty chemicals, and polymers, using biological processes. These chemicals serve as building blocks for various industries, including plastics, pharmaceuticals, and consumer products.
  • Biomaterials: materials derived from biological sources, such as bioplastics, bio-based composites, and biominerals. These materials find applications in packaging, construction, and medical devices.
  • Agricultural biologicals: production of biopesticides, biofertilizers, and other biological products used in agriculture to enhance crop productivity and protect against pests and diseases.
  • Flavors and fragrances: Biomanufacturing processes are used to produce natural flavors, fragrances, and other sensory ingredients for the food, beverage, and cosmetic industries.
  • Synthetic biology products: production of novel products and materials designed using synthetic biology principles, such as engineered microorganisms, biosynthetic pathways, and genetic circuits.

 

These sub-markets represent the diverse applications of biomanufacturing and highlight the growing importance of biological processes in various sectors of the economy. As technology advances, new sub-markets may emerge, further expanding the scope of biomanufacturing.

The Global Biomanufacturing Markets 2024-2035 is a comprehensive market report that explores the rapidly evolving landscape of biomanufacturing technologies and applications. This in-depth analysis covers key sectors such as biopharmaceuticals, industrial enzymes, biofuels, bioplastics, biochemicals, and bio-agritech, providing insights into market trends, growth opportunities, and the competitive landscape. The report offers a detailed overview of biomanufacturing processes, technologies, and host organisms, highlighting the importance of this industry in the global economy. It covers production methods, including microbial fermentation, mammalian cell culture, and plant-based systems, as well as upstream and downstream processing technologies.

The report features profiles of over 1,000 companies at the forefront of biomanufacturing innovation, offering valuable insights into their technologies, products, and strategic initiatives. Companies profiled include  Aanika Biosciences, Amyris, BBGI, Biovectra, Bucha Bio, Byogy Renewables, Cascade Biocatalysts, Constructive Bio, Debut Biotechnology, Enginzyme AB, eversyn, Erebagen, Eligo Bioscience, Evolutor, EV Biotech, FabricNano, Ginkgo Bioworks, Hyfé, Invizyne Technologies, LanzaTech, Lygos, Mammoth Biosciences, Novozymes A/S, NTx, Origin Materials, Pow.bio, Protein Evolution, Solugen, Synthego, Taiwan Bio-Manufacturing Corp. (TBMC), Twist Bioscience, Uluu, Van Heron Labs, Verde Bioresins, and ZymoChem.

 

 

 

1             EXECUTIVE SUMMARY 

  • 1.1         Definition and Scope of Biomanufacturing       49
  • 1.2         Overview of Biomanufacturing Processes         49
  • 1.3         Key Components of Biomanufacturing               52
  • 1.4         Importance of Biomanufacturing in the Global Economy           53
    • 1.4.1     Role in Healthcare and Pharmaceutical Industries      53
    • 1.4.2     Impact on Industrial Biotechnology and Sustainability               53
  • 1.5         Markets               54
    • 1.5.1     Healthcare and Pharmaceuticals         54
    • 1.5.2     Food and Beverage       55
    • 1.5.3     Agriculture and Animal Health 56
    • 1.5.4     Industrial Biotechnology            57
    • 1.5.5     Environmental Biotechnology 57

 

2             PRODUCTION 

  • 2.1         Microbial Fermentation              58
  • 2.2         Mammalian Cell Culture            59
  • 2.3         Plant Cell Culture           60
  • 2.4         Insect Cell Culture        60
  • 2.5         Transgenic Animals      61
  • 2.6         Transgenic Plants          62
  • 2.7         Technologies    63
    • 2.7.1     Upstream Processing  63
      • 2.7.1.1 Cell Culture       63
        • 2.7.1.1.1             Overview            63
        • 2.7.1.1.2             Types of Cell Culture Systems 63
        • 2.7.1.1.3             Factors Affecting Cell Culture Performance    64
        • 2.7.1.1.4             Advances in Cell Culture Technology   64
          • 2.7.1.1.4.1         Single-use systems       64
          • 2.7.1.1.4.2         Process analytical technology (PAT)     64
          • 2.7.1.1.4.3         Cell line development 65
    • 2.7.2     Fermentation   65
      • 2.7.2.1 Overview            65
        • 2.7.2.1.1             Types of Fermentation Processes         65
        • 2.7.2.1.2             Factors Affecting Fermentation Performance 65
        • 2.7.2.1.3             Advances in Fermentation Technology               66
          • 2.7.2.1.3.1         High-cell-density fermentation               66
          • 2.7.2.1.3.2         Continuous processing               66
          • 2.7.2.1.3.3         Metabolic engineering 66
    • 2.7.3     Downstream Processing            67
      • 2.7.3.1 Purification       67
        • 2.7.3.1.1             Overview            67
        • 2.7.3.1.2             Types of Purification Methods 67
        • 2.7.3.1.3             Factors Affecting Purification Performance     67
        • 2.7.3.1.4             Advances in Purification Technology   68
          • 2.7.3.1.4.1         Affinity chromatography            68
          • 2.7.3.1.4.2         Membrane chromatography     68
          • 2.7.3.1.4.3         Continuous chromatography   68
    • 2.7.4     Formulation      69
      • 2.7.4.1 Overview            69
        • 2.7.4.1.1             Types of Formulation Methods 69
        • 2.7.4.1.2             Factors Affecting Formulation Performance    69
        • 2.7.4.1.3             Advances in Formulation Technology  70
          • 2.7.4.1.3.1         Controlled release        70
          • 2.7.4.1.3.2         Nanoparticle formulation          70
        • 2.7.4.1.3.3         3D printing         70
    • 2.7.5     Bioprocess Development          70
      • 2.7.5.1 Scale-up             70
        • 2.7.5.1.1             Overview            70
        • 2.7.5.1.2             Factors Affecting Scale-up Performance           70
        • 2.7.5.1.3             Scale-up Strategies      71
      • 2.7.5.2 Optimization    71
        • 2.7.5.2.1             Overview            71
        • 2.7.5.2.2             Factors Affecting Optimization Performance  71
        • 2.7.5.2.3             Optimization Strategies             71
    • 2.7.6     Analytical Methods       72
      • 2.7.6.1 Quality Control                72
        • 2.7.6.1.1             Overview            72
        • 2.7.6.1.2             Types of Quality Control Tests 72
        • 2.7.6.1.3             Factors Affecting Quality Control Performance              72
      • 2.7.6.2 Characterization            73
        • 2.7.6.2.1             Overview            73
        • 2.7.6.2.2             Types of Characterization Methods      73
        • 2.7.6.2.3             Factors Affecting Characterization Performance          73
  • 2.8         Scale of Production      74
    • 2.8.1     Laboratory Scale            74
      • 2.8.1.1 Overview            74
      • 2.8.1.2 Scale and Equipment   74
      • 2.8.1.3 Advantages       74
      • 2.8.1.4 Disadvantages 74
    • 2.8.2     Pilot Scale         75
      • 2.8.2.1 Overview            75
      • 2.8.2.2 Scale and Equipment   75
      • 2.8.2.3 Advantages       75
      • 2.8.2.4 Disadvantages 75
    • 2.8.3     Commercial Scale        75
      • 2.8.3.1 Overview            76
      • 2.8.3.2 Scale and Equipment   76
      • 2.8.3.3 Advantages       76
      • 2.8.3.4 Disadvantages 76
  • 2.9         Mode of Operation        77
    • 2.9.1     Batch Production           77
      • 2.9.1.1 Overview            77
      • 2.9.1.2 Advantages       78
      • 2.9.1.3 Disadvantages 78
      • 2.9.1.4 Applications     78
    • 2.9.2     Fed-batch Production  78
      • 2.9.2.1 Overview            78
      • 2.9.2.2 Advantages       78
      • 2.9.2.3 Disadvantages 79
      • 2.9.2.4 Applications     79
    • 2.9.3     Continuous Production               79
      • 2.9.3.1 Overview            79
      • 2.9.3.2 Advantages       79
      • 2.9.3.3 Disadvantages 79
      • 2.9.3.4 Applications     79
    • 2.9.4     Cell factories for biomanufacturing      80
    • 2.9.5     Perfusion Culture           81
      • 2.9.5.1 Overview            81
      • 2.9.5.2 Advantages       81
  • 2.10       Host Organisms              83

 

3             BIOPHARMACEUTICALS            

  • 3.1         Technology/materials analysis               84
    • 3.1.1     Monoclonal Antibodies (mAbs)               85
    • 3.1.2     Recombinant Proteins 85
    • 3.1.3     Vaccines            86
    • 3.1.4     Cell and Gene Therapies            86
    • 3.1.5     Blood Factors  87
    • 3.1.6     Tissue Engineering Products    88
    • 3.1.7     Nucleic Acid Therapeutics        89
    • 3.1.8     Peptide Therapeutics   89
    • 3.1.9     Biosimilars and Biobetters        89
    • 3.1.10   Nanobodies and Antibody Fragments  89
    • 3.1.11   Synthetic biology           90
    • 3.1.12   Generative biology        91
  • 3.2         Market analysis               92
    • 3.2.1     Key players and competitive landscape             92
    • 3.2.2     Market Growth Drivers and Trends        95
    • 3.2.3     Regulations       97
    • 3.2.4     Value chain       98
    • 3.2.5     Future outlook 100
    • 3.2.6     Addressable Market Size           101
    • 3.2.7     Risks and Opportunities             102
    • 3.2.8     Global revenues             103
      • 3.2.8.1 By application market 104
      • 3.2.8.2 By regional market        105
  • 3.3         Company profiles          106 (113 company profiles)

 

4             INDUSTRIAL ENZYMES 

  • 4.1         Technology/materials analysis               189
    • 4.1.1     Detergent Enzymes       189
    • 4.1.2     Food Processing Enzymes         190
    • 4.1.3     Textile Processing Enzymes     191
    • 4.1.4     Paper and Pulp Processing Enzymes   192
    • 4.1.5     Leather Processing Enzymes   193
    • 4.1.6     Biofuel Production Enzymes    194
    • 4.1.7     Animal Feed Enzymes 194
    • 4.1.8     Pharmaceutical and Diagnostic Enzymes         195
    • 4.1.9     Waste Management and Bioremediation Enzymes      196
    • 4.1.10   Agriculture and Crop Improvement Enzymes  197
  • 4.2         Market analysis               199
    • 4.2.1     Key players and competitive landscape             199
    • 4.2.2     Market Growth Drivers and Trends        201
    • 4.2.3     Regulations       203
    • 4.2.4     Value chain       204
    • 4.2.5     Future outlook 206
    • 4.2.6     Addressable Market Size           207
    • 4.2.7     Risks and Opportunities             208
    • 4.2.8     Global revenues             209
      • 4.2.8.1 By application market 209
      • 4.2.8.2 By regional market        210
  • 4.3         Companies profiles      212 (75 company profiles)

 

5             BIOFUELS          

  • 5.1         Technology/materials analysis               271
    • 5.1.1     Role in the circular economy   272
    • 5.1.2     The global biofuels market        273
    • 5.1.3     Feedstocks       274
      • 5.1.3.1 First-generation (1-G)  275
      • 5.1.3.2 Second-generation (2-G)            276
        • 5.1.3.2.1             Lignocellulosic wastes and residues    277
        • 5.1.3.2.2             Biorefinery lignin            278
      • 5.1.3.3 Third-generation (3-G) 282
        • 5.1.3.3.1             Algal biofuels   282
          • 5.1.3.3.1.1         Properties          283
          • 5.1.3.3.1.2         Advantages       283
      • 5.1.3.4 Fourth-generation (4-G)              285
      • 5.1.3.5 Advantages and disadvantages, by generation               285
    • 5.1.4     Bioethanol         286
      • 5.1.4.1 First-generation bioethanol (from sugars and starches)             286
      • 5.1.4.2 Second-generation bioethanol (from lignocellulosic biomass)               287
      • 5.1.4.3 Third-generation bioethanol (from algae)           287
    • 5.1.5     Biodiesel            287
      • 5.1.5.1 Biodiesel by generation               287
      • 5.1.5.2 SWOT analysis 288
      • 5.1.5.3 Production of biodiesel and other biofuels        289
        • 5.1.5.3.1             Pyrolysis of biomass     290
        • 5.1.5.3.2             Vegetable oil transesterification            292
        • 5.1.5.3.3             Vegetable oil hydrogenation (HVO)       294
          • 5.1.5.3.3.1         Production process       294
        • 5.1.5.3.4             Biodiesel from tall oil   295
        • 5.1.5.3.5             Fischer-Tropsch BioDiesel        295
        • 5.1.5.3.6             Hydrothermal liquefaction of biomass 297
        • 5.1.5.3.7             CO2 capture and Fischer-Tropsch (FT)                298
        • 5.1.5.3.8             Dymethyl ether (DME)  298
      • 5.1.5.4 Prices  298
      • 5.1.5.5 Global production and consumption   299
    • 5.1.6     Biogas  301
      • 5.1.6.1 Feedstocks       303
      • 5.1.6.2 Biomethane      304
        • 5.1.6.2.1             Production pathways   306
          • 5.1.6.2.1.1         Landfill gas recovery    306
          • 5.1.6.2.1.2         Anaerobic digestion      307
          • 5.1.6.2.1.3         Thermal gasification    307
      • 5.1.6.3 SWOT analysis 308
      • 5.1.6.4 Global production          309
      • 5.1.6.5 Prices  309
        • 5.1.6.5.1             Raw Biogas        309
        • 5.1.6.5.2             Upgraded Biomethane 309
      • 5.1.6.6 Bio-LNG             310
        • 5.1.6.6.1             Markets               310
          • 5.1.6.6.1.1         Trucks  310
          • 5.1.6.6.1.2         Marine 310
        • 5.1.6.6.2             Production        310
        • 5.1.6.6.3             Plants  311
      • 5.1.6.7 bio-CNG (compressed natural gas derived from biogas)            311
      • 5.1.6.8 Carbon capture from biogas     311
      • 5.1.6.9 Biosyngas          312
        • 5.1.6.9.1             Production        312
        • 5.1.6.9.2             Prices  313
    • 5.1.7     Biobutanol         314
      • 5.1.7.1 Production        315
      • 5.1.7.2 Prices  316
    • 5.1.8     Biohydrogen     316
      • 5.1.8.1 Description       316
      • 5.1.8.2 SWOT analysis 317
      • 5.1.8.3 Production of biohydrogen from biomass          318
        • 5.1.8.3.1             Biological Conversion Routes  319
          • 5.1.8.3.1.1         Bio-photochemical Reaction   319
          • 5.1.8.3.1.2         Fermentation and Anaerobic Digestion              319
        • 5.1.8.3.2             Thermochemical conversion routes     319
          • 5.1.8.3.2.1         Biomass Gasification  319
          • 5.1.8.3.2.2         Biomass Pyrolysis         320
          • 5.1.8.3.2.3         Biomethane Reforming               320
      • 5.1.8.4 Applications     320
      • 5.1.8.5 Prices  321
    • 5.1.9     Biomethanol    321
      • 5.1.9.1 SWOT analysis 322
        • 5.1.9.2 Methanol-to gasoline technology           323
      • 5.1.9.2.1             Production processes  324
        • 5.1.9.2.1.1         Anaerobic digestion      325
        • 5.1.9.2.1.2         Biomass gasification   325
        • 5.1.9.2.1.3         Power to Methane         326
    • 5.1.10   Bio-oil and Biochar        327
      • 5.1.10.1               Advantages of bio-oils 327
      • 5.1.10.2               Production        328
        • 5.1.10.2.1           Fast Pyrolysis   328
        • 5.1.10.2.2           Costs of production      329
        • 5.1.10.2.3           Upgrading          329
      • 5.1.10.3               SWOT analysis 330
      • 5.1.10.4               Applications     331
      • 5.1.10.5               Bio-oil producers            331
      • 5.1.10.6               Prices  332
      • 5.1.10.7               Biochar               333
    • 5.1.11   Renewable Diesel and Jet Fuel 334
      • 5.1.11.1               Renewable diesel          334
        • 5.1.11.1.1           Production        335
        • 5.1.11.1.2           SWOT analysis 335
        • 5.1.11.1.3           Global consumption     336
        • 5.1.11.1.4           Prices  338
      • 5.1.11.2               Bio-aviation fuel (bio-jet fuel, sustainable aviation fuel, renewable jet fuel or aviation biofuel)                339
        • 5.1.11.2.1           Description       339
        • 5.1.11.2.2           SWOT analysis 339
        • 5.1.11.2.3           Global production and consumption   340
        • 5.1.11.2.4           Production pathways   340
        • 5.1.11.2.5           Prices  342
        • 5.1.11.2.6           Bio-aviation fuel production capacities              343
        • 5.1.11.2.7           Challenges        344
        • 5.1.11.2.8           Global consumption     344
    • 5.1.12   Algal biofuels   345
      • 5.1.12.1               Conversion pathways  345
      • 5.1.12.2               SWOT analysis 346
      • 5.1.12.3               Production        347
      • 5.1.12.4               Market challenges         348
      • 5.1.12.5               Prices  349
      • 5.1.12.6               Producers          349
  • 5.2         Market analysis               351
    • 5.2.1     Key players and competitive landscape             351
    • 5.2.2     Market Growth Drivers and Trends        353
    • 5.2.3     Regulations       355
    • 5.2.4     Value chain       356
    • 5.2.5     Future outlook 358
    • 5.2.6     Addressable Market Size           359
    • 5.2.7     Risks and Opportunities             361
    • 5.2.8     Global revenues             361
      • 5.2.8.1 By biofuel type 362
      • 5.2.8.2 By regional market        363
  • 5.3         Company profiles          364 (213 company profiles)

 

6             BIOPLASTICS   

  • 6.1         Technology/materials analysis               520
    • 6.1.1     Polylactic acid (PLA)    521
    • 6.1.2     Polyhydroxyalkanoates (PHAs)               522
      • 6.1.2.1 Polyhydroxybutyrate (PHB)       522
      • 6.1.2.2 Polyhydroxyvalerate (PHV)        524
    • 6.1.3     Bio-based polyethylene (PE)     525
    • 6.1.4     Bio-based polyethylene terephthalate (PET)    526
    • 6.1.5     Bio-based polyurethanes (PUs)               528
    • 6.1.6     Starch-based plastics 529
    • 6.1.7     Cellulose-based plastics           530
  • 6.2         Market analysis               531
    • 6.2.1     Key players and competitive landscape             531
    • 6.2.2     Market Growth Drivers and Trends        533
    • 6.2.3     Regulations       535
    • 6.2.4     Value chain       536
    • 6.2.5     Future outlook 538
    • 6.2.6     Addressable Market Size           539
    • 6.2.7     Risks and Opportunities             541
    • 6.2.8     Global revenues             541
      • 6.2.8.1 By type 541
      • 6.2.8.2 By application market 542
      • 6.2.8.3 By regional market        543
  • 6.3         Company profiles          545 (520 company profiles)

 

7             BIOCHEMICALS             

  • 7.1         Technology/materials analysis               922
    • 7.1.1     Organic acids   922
      • 7.1.1.1 Lactic acid        922
      • 7.1.1.2 Succinic acid   922
      • 7.1.1.3 Itaconic acid    922
      • 7.1.1.4 Citric acid          922
      • 7.1.1.5 Acetic acid        922
    • 7.1.2     Amino acids      922
      • 7.1.2.1 Glutamic acid  922
      • 7.1.2.2 Lysine  922
      • 7.1.2.3 Threonine           923
      • 7.1.2.4 Methionine        923
    • 7.1.3     Alcohols             923
      • 7.1.3.1 Ethanol                923
      • 7.1.3.2 Butanol               923
      • 7.1.3.3 Isobutanol         923
      • 7.1.3.4 Propanediol      923
    • 7.1.4     Surfactants       923
      • 7.1.4.1 Biosurfactants (e.g., rhamnolipids, sophorolipids)        923
      • 7.1.4.2 Alkyl polyglucosides (APGs)      924
    • 7.1.5     Solvents             924
      • 7.1.5.1 Ethyl lactate     924
      • 7.1.5.2 Dimethyl carbonate      924
      • 7.1.5.3 Glycerol              924
    • 7.1.6     Flavors and fragrances 924
      • 7.1.6.1 Vanillin 924
      • 7.1.6.2 Nootkatone       924
      • 7.1.6.3 Limonene          924
    • 7.1.7     Bio-based monomers and intermediates          924
      • 7.1.7.1 Succinic acid   924
      • 7.1.7.2 1,4-Butanediol (BDO)   924
      • 7.1.7.3 Isoprene             924
      • 7.1.7.4 Ethylene             924
      • 7.1.7.5 Propylene          924
      • 7.1.7.6 Adipic acid        924
      • 7.1.7.7 Acrylic acid       924
      • 7.1.7.8 Sebacic acid    925
    • 7.1.8     Bio-based polymers     925
      • 7.1.8.1 Polybutylene succinate (PBS)  925
      • 7.1.8.2 Polyamides (nylons)     925
      • 7.1.8.3 Polyethylene furanoate (PEF)   925
      • 7.1.8.4 Polytrimethylene terephthalate (PTT)   925
      • 7.1.8.5 Polyethylene isosorbide terephthalate (PEIT)  925
    • 7.1.9     Bio-based composites and blends        925
      • 7.1.9.1 Wood-plastic composites (WPCs)         925
      • 7.1.9.2 Biofiller-reinforced plastics      925
      • 7.1.9.3 Biofiber-reinforced plastics      925
      • 7.1.9.4 Polymer blends with bio-based components   925
  • 7.2         Market analysis               925
    • 7.2.1     Key players and competitive landscape             925
    • 7.2.2     Market Growth Drivers and Trends        928
    • 7.2.3     Regulations       930
    • 7.2.4     Value chain       931
    • 7.2.5     Future outlook 933
    • 7.2.6     Addressable Market Size           933
    • 7.2.7     Risks and Opportunities             935
    • 7.2.8     Global revenues             936
      • 7.2.8.1 By type 936
      • 7.2.8.2 By application market 937
      • 7.2.8.3 By regional market        938
  • 7.3         Company profiles          939 (117 company profiles)

 

8             BIO-AGRITECH 

  • 8.1         Technology/materials analysis               1015
    • 8.1.1     Biopesticides   1016
      • 8.1.1.1 Microbial pesticides     1017
      • 8.1.1.2 Biochemical pesticides              1018
      • 8.1.1.3 Plant-incorporated protectants (PIPs) 1019
    • 8.1.2     Biofertilizers     1019
    • 8.1.3     Biostimulants  1020
      • 8.1.3.1 Microbial biostimulants             1021
      • 8.1.3.2 Non-microbial biostimulants  1023
    • 8.1.4     Agricultural Enzymes   1024
  • 8.2         Market analysis               1025
    • 8.2.1     Key players and competitive landscape             1025
    • 8.2.2     Market Growth Drivers and Trends        1027
    • 8.2.3     Regulations       1029
    • 8.2.4     Value chain       1030
    • 8.2.5     Future outlook 1032
    • 8.2.6     Addressable Market Size           1033
    • 8.2.7     Risks and Opportunities             1035
    • 8.2.8     Global revenues             1036
      • 8.2.8.1 By application market 1036
      • 8.2.8.2 By regional market        1037
  • 8.3         Company profiles          1038 (151 company profiles)

 

9             RESEARCH METHODOLOGY   

 

10           REFERENCES   

 

List of Tables

  • Table 1. Biomanufacturing categories. 49
  • Table 2. Overview of Biomanufacturing Processes.      50
  • Table 3. Continuous vs batch biomanufacturing            51
  • Table 4. Key Components of Biomanufacturing.            52
  • Table 5. Key fermentation parameters in batch vs continuous biomanufacturing processes. 77
  • Table 6.  Major microbial cell factories used in industrial biomanufacturing.  80
  • Table 7. Host organisms commonly used in biomanufacturing.             83
  • Table 8. Key players in biopharmaceuticals.    93
  • Table 9. Market Growth Drivers and Trends in Biopharmaceuticals.    95
  • Table 10. Biopharmaceuticals Regulations.     97
  • Table 11. Value chain: Biopharmaceuticals.    98
  • Table 12. Addressable market size for biopharmaceuticals.    101
  • Table 13. Risks and Opportunities in biopharmaceuticals.       102
  • Table 14. Global revenues for biopharmaceuticals, by applications market (2020-2035), billions USD.            104
  • Table 15. Global revenues for biopharmaceuticals, by regional market (2020-2035), billions USD.      105
  • Table 16. Key players in industrial enzymes.    199
  • Table 17. Market Growth Drivers and Trends in industrial enzymes.     201
  • Table 18. Industrial enzymes Regulations.        203
  • Table 19. Value chain: Industrial enzymes.       204
  • Table 20. Addressable market size for industrial enzymes.       207
  • Table 21. Risks and Opportunities in industrial enzymes.          208
  • Table 22. Global revenues for industrial enzymes, by applications market (2020-2035), billions USD.               210
  • Table 23. Global revenues for industrial enzymes, by regional market (2020-2035), billions USD.        211
  • Table 24. Comparison of biofuels.         272
  • Table 25. Classification of biomass feedstock.               274
  • Table 26. Biorefinery feedstocks.           274
  • Table 27. Feedstock conversion pathways.      275
  • Table 28. First-Generation Feedstocks.              275
  • Table 29.  Lignocellulosic ethanol plants and capacities.          278
  • Table 30. Comparison of pulping and biorefinery lignins.          279
  • Table 31. Commercial and pre-commercial biorefinery lignin production facilities and  processes     280
  • Table 32. Operating and planned lignocellulosic biorefineries and industrial flue gas-to-ethanol.       281
  • Table 33. Properties of microalgae and macroalgae.   283
  • Table 34. Yield of algae and other biodiesel crops.        284
  • Table 35. Advantages and disadvantages of biofuels, by generation.   285
  • Table 36. Biodiesel by generation.         287
  • Table 37. Biodiesel production techniques.      290
  • Table 38. Summary of pyrolysis technique under different operating conditions.          290
  • Table 39. Biomass materials and their bio-oil yield.      291
  • Table 40. Biofuel production cost from the biomass pyrolysis process.              292
  • Table 41. Properties of vegetable oils in comparison to diesel.               293
  • Table 42. Main producers of HVO and capacities.         295
  • Table 43. Example commercial Development of BtL processes.            296
  • Table 44. Pilot or demo projects for biomass to liquid (BtL) processes.              296
  • Table 45. Global biodiesel consumption, 2010-2035 (M litres/year).   301
  • Table 46. Biogas feedstocks.    304
  • Table 47. Existing and planned bio-LNG production plants.      311
  • Table 48. Methods for capturing carbon dioxide from biogas.  312
  • Table 49. Comparison of different Bio-H2 production pathways.           318
  • Table 50. Markets and applications for biohydrogen.   321
  • Table 51. Comparison of biogas, biomethane and natural gas.               324
  • Table 52. Typical composition and physicochemical properties reported for bio-oils and heavy petroleum-derived oils.      328
  • Table 53. Properties and characteristics of pyrolysis liquids derived from biomass versus a fuel oil.  328
  • Table 54. Main techniques used to upgrade bio-oil into higher-quality fuels.   329
  • Table 55. Markets and applications for bio-oil.                331
  • Table 56. Bio-oil producers.      331
  • Table 57. Summary of applications of biochar in energy.           333
  • Table 58. Global renewable diesel consumption, 2010-2035 (M litres/year).   337
  • Table 59. Renewable diesel price ranges.          338
  • Table 60. Advantages and disadvantages of Bio-aviation fuel. 339
  • Table 61. Production pathways for Bio-aviation fuel.   341
  • Table 62. Current and announced Bio-aviation fuel facilities and capacities. 343
  • Table 63. Global bio-jet fuel consumption 2019-2035 (Million litres/year).       345
  • Table 64. Algae-derived biofuel producers.       350
  • Table 65. Key players in biofuels.           351
  • Table 66. Market Growth Drivers and Trends in biofuels.            353
  • Table 67. Biofuels Regulations.               355
  • Table 68. Value chain: Biofuels.              356
  • Table 69. Addressable market size for biofuels.              359
  • Table 70. Risks and Opportunities in biofuels  361
  • Table 71. Global revenues for biofuels, by type (2020-2035), billions USD.       362
  • Table 72. Global revenues for biofuels, by regional market (2020-2035), billions USD.               363
  • Table 73. Granbio Nanocellulose Processes.  431
  • Table 74. Key players in Bioplastics.     531
  • Table 75. Market Growth Drivers and Trends in Bioplastics.     533
  • Table 76. Bioplastics Regulations.         535
  • Table 77. Value chain: Bioplastics.       536
  • Table 78. Addressable market size for Bioplastics.       539
  • Table 79. Risks and Opportunities in Bioplastics.          541
  • Table 80. Global revenues for bioplastics, by type (2020-2035), billions USD. 541
  • Table 81. Global revenues for bioplastics, by applications market (2020-2035), billions USD.                542
  • Table 82. Global revenues for bioplastics, by regional market (2020-2035), billions USD.         543
  • Table 83. Lactips plastic pellets.            731
  • Table 84. Oji Holdings CNF products.  798
  • Table 85. Key players in Biochemicals.               925
  • Table 86. Market Growth Drivers and Trends in Biochemicals. 928
  • Table 87. Biochemicals Regulations.   930
  • Table 88. Value chain: Biochemicals.  931
  • Table 89. Addressable market size for Biochemicals. 934
  • Table 90. Risks and Opportunities in Biochemicals.    935
  • Table 91. Global revenues for biochemicals, by type (2020-2035), billions USD.           936
  • Table 92. Global revenues for biochemicals, by applications market (2020-2035), billions USD.          937
  • Table 93. Global revenues for biochemicals, by regional market (2020-2035), billions USD.   938
  • Table 94. Key players in Bio Agritech.   1025
  • Table 95. Market Growth Drivers and Trends in Bio Agritech     1027
  • Table 96. Bio Agritech Regulations.       1029
  • Table 97. Value chain: Bio Agritech.      1030
  • Table 98. Addressable market size for Bio Agritech.     1033
  • Table 99. Risks and Opportunities in Bio Agritech.        1035
  • Table 100. Global revenues for Bio Agritech products, by applications market (2020-2035), billions USD.       1036
  • Table 101. Global revenues for Bio Agritech products, by regional market (2020-2035), billions USD. 1037

 

List of Figures

  • Figure 1. The design-make-test-learn loop of generative biology.          92
  • Figure 2. Global revenues for biopharmaceuticals, by applications market (2020-2035), billions USD.             105
  • Figure 3. Global revenues for biopharmaceuticals, by regional market (2020-2035), billions USD.       106
  • Figure 4. XtalPi’s automated and robot-run workstations.         187
  • Figure 5. Global revenues for industrial enzymes, by applications market (2020-2035), billions USD. 210
  • Figure 6. Global revenues for industrial enzymes, by regional market (2020-2035), billions USD.         211
  • Figure 7. Light Bio Bioluminescent plants.        232
  • Figure 8. Corbion FDCA production process.   239
  • Figure 9. Light Bio Bioluminescent plants.        267
  • Figure 10.  Schematic of a biorefinery for production of carriers and chemicals.           279
  • Figure 11. Hydrolytic lignin powder.      282
  • Figure 12. SWOT analysis for biodiesel.              289
  • Figure 13. Flow chart for biodiesel production.               293
  • Figure 14. Biodiesel (B20) average prices, current and historical, USD/litre.   299
  • Figure 15. Global biodiesel consumption, 2010-2035 (M litres/year).  300
  • Figure 16. Biogas and biomethane pathways. 303
  • Figure 17. Overview of biogas utilization.           305
  • Figure 18. Biogas and biomethane pathways. 306
  • Figure 19. Schematic overview of anaerobic digestion process for biomethane production.   307
  • Figure 20. Schematic overview of biomass gasification for biomethane production.   308
  • Figure 21. SWOT analysis for biogas.    309
  • Figure 22. Total syngas market by product in MM Nm³/h of Syngas, 2021.         313
  • Figure 23. Properties of petrol and biobutanol.               314
  • Figure 24. Biobutanol production route.             315
  • Figure 25. SWOT analysis for biohydrogen.       318
  • Figure 26. SWOT analysis biomethanol.             323
  • Figure 27. Renewable Methanol Production Processes from Different Feedstocks.    324
  • Figure 28. Production of biomethane through anaerobic digestion and upgrading.       325
  • Figure 29. Production of biomethane through biomass gasification and methanation.              326
  • Figure 30. Production of biomethane through the Power to methane process.               326
  • Figure 31. Bio-oil upgrading/fractionation techniques.               329
  • Figure 32. SWOT analysis for bio-oils.  331
  • Figure 33. SWOT analysis for renewable iesel. 336
  • Figure 34. Global renewable diesel consumption, 2010-2035 (M litres/year). 337
  • Figure 35. SWOT analysis for Bio-aviation fuel.               340
  • Figure 36. Global bio-jet fuel consumption to 2019-2035 (Million litres/year). 344
  • Figure 37.  Pathways for algal biomass conversion to biofuels.               346
  • Figure 38. SWOT analysis for algae-derived biofuels.  347
  • Figure 39. Algal biomass conversion process for biofuel production.  348
  • Figure 40. Global revenues for biofuels, by type (2020-2035), billions USD.     362
  • Figure 41. Global revenues for biofuels, by regional market (2020-2035), billions USD.             363
  • Figure 42. ANDRITZ Lignin Recovery process.  371
  • Figure 43. ChemCyclingTM prototypes.              377
  • Figure 44. ChemCycling circle by BASF.             377
  • Figure 45. FBPO process            389
  • Figure 46. Direct Air Capture Process. 393
  • Figure 47. CRI process.               395
  • Figure 48. Cassandra Oil  process.        398
  • Figure 49. Colyser process.       406
  • Figure 50. ECFORM electrolysis reactor schematic.    410
  • Figure 51. Dioxycle modular electrolyzer.         411
  • Figure 52. Domsjö process.      413
  • Figure 53. FuelPositive system.              425
  • Figure 54. INERATEC unit.          442
  • Figure 55. Infinitree swing method.       443
  • Figure 56. Audi/Krajete unit.     449
  • Figure 57. Enfinity cellulosic ethanol technology process.        475
  • Figure 58: Plantrose process.   483
  • Figure 59. Sunfire process for Blue Crude production. 500
  • Figure 60. Takavator.    504
  • Figure 61. O12 Reactor.              507
  • Figure 62. Sunglasses with lenses made from CO2-derived materials.              507
  • Figure 63. CO2 made car part. 508
  • Figure 64. The Velocys process.              510
  • Figure 65. Goldilocks process and applications.            513
  • Figure 66. The Proesa® Process.             514
  • Figure 67. Global revenues for bioplastics, by type (2020-2035), billions USD.               542
  • Figure 68. Global revenues for bioplastics, by applications market (2020-2035), billions USD.              543
  • Figure 69. Global revenues for bioplastics, by regional market (2020-2035), billions USD.       544
  • Figure 70. Pluumo.        549
  • Figure 71. ANDRITZ Lignin Recovery process.  557
  • Figure 72. Anpoly cellulose nanofiber hydrogel.             559
  • Figure 73. MEDICELLU™.            559
  • Figure 74. Asahi Kasei CNF fabric sheet.            568
  • Figure 75. Properties of Asahi Kasei cellulose nanofiber nonwoven fabric.       568
  • Figure 76. CNF nonwoven fabric.           569
  • Figure 77. Roof frame made of natural fiber.    579
  • Figure 78. Beyond Leather Materials product. 582
  • Figure 79. BIOLO e-commerce mailer bag made from PHA.     588
  • Figure 80. Reusable and recyclable foodservice cups, lids, and straws from Joinease Hong Kong Ltd., made with plant-based NuPlastiQ BioPolymer from BioLogiQ, Inc.             589
  • Figure 81. Fiber-based screw cap.         601
  • Figure 82. formicobio™ technology.      620
  • Figure 83. nanoforest-S.             622
  • Figure 84. nanoforest-PDP.       623
  • Figure 85. nanoforest-MB.         623
  • Figure 86. sunliquid® production process.         631
  • Figure 87. CuanSave film.          634
  • Figure 88. Celish.           635
  • Figure 89. Trunk lid incorporating CNF.               637
  • Figure 90. ELLEX products.        638
  • Figure 91. CNF-reinforced PP compounds.       639
  • Figure 92. Kirekira! toilet wipes.              639
  • Figure 93. Color CNF.   640
  • Figure 94. Rheocrysta spray.    645
  • Figure 95. DKS CNF products.  646
  • Figure 96. Domsjö process.      647
  • Figure 97. Mushroom leather.  657
  • Figure 98. CNF based on citrus peel.    658
  • Figure 99. Citrus cellulose nanofiber.  659
  • Figure 100. Filler Bank CNC products. 669
  • Figure 101. Fibers on kapok tree and after processing.               672
  • Figure 102.  TMP-Bio Process. 674
  • Figure 103. Flow chart of the lignocellulose biorefinery pilot plant in Leuna.    675
  • Figure 104. Water-repellent cellulose. 677
  • Figure 105. Cellulose Nanofiber (CNF) composite with polyethylene (PE).        678
  • Figure 106. PHA production process.   680
  • Figure 107. CNF products from Furukawa Electric.      680
  • Figure 108. AVAPTM process.  690
  • Figure 109. GreenPower+™ process.    690
  • Figure 110. Cutlery samples (spoon, knife, fork) made of nano cellulose and biodegradable plastic composite materials.          693
  • Figure 111. Non-aqueous CNF dispersion "Senaf" (Photo shows 5% of plasticizer).    695
  • Figure 112. CNF gel.      702
  • Figure 113. Block nanocellulose material.        702
  • Figure 114. CNF products developed by Hokuetsu.      703
  • Figure 115. Marine leather products.    706
  • Figure 116. Inner Mettle Milk products.               709
  • Figure 117. Kami Shoji CNF products. 720
  • Figure 118. Dual Graft System.               722
  • Figure 119. Engine cover utilizing Kao CNF composite resins. 723
  • Figure 120. Acrylic resin blended with modified CNF (fluid) and its molded product (transparent film), and image obtained with AFM (CNF 10wt% blended).         724
  • Figure 121. Kel Labs yarn.          724
  • Figure 122. 0.3% aqueous dispersion of sulfated esterified CNF and dried transparent film (front side).           728
  • Figure 123. Lignin gel.  737
  • Figure 124. BioFlex process.     740
  • Figure 125. Nike Algae Ink graphic tee. 741
  • Figure 126. LX Process.               745
  • Figure 127. Made of Air's HexChar panels.        748
  • Figure 128. TransLeather.          749
  • Figure 129. Chitin nanofiber product.   753
  • Figure 130. Marusumi Paper cellulose nanofiber products.      755
  • Figure 131. FibriMa cellulose nanofiber powder.            756
  • Figure 132. METNIN™ Lignin refining technology.           759
  • Figure 133. IPA synthesis method.         763
  • Figure 134. MOGU-Wave panels.           766
  • Figure 135. CNF slurries.            766
  • Figure 136. Range of CNF products.      767
  • Figure 137. Reishi.         770
  • Figure 138. Compostable water pod.    787
  • Figure 139. Leather made from leaves.               788
  • Figure 140. Nike shoe with beLEAF™.   788
  • Figure 141. CNF clear sheets.  798
  • Figure 142. Oji Holdings CNF polycarbonate product. 799
  • Figure 143. Enfinity cellulosic ethanol technology process.     812
  • Figure 144. Fabric consisting of 70 per cent wool and 30 per cent Qmilk.          817
  • Figure 145. XCNF.          824
  • Figure 146: Plantrose process. 825
  • Figure 147. LOVR hemp leather.             828
  • Figure 148. CNF insulation flat plates. 830
  • Figure 149. Hansa lignin.            837
  • Figure 150. Manufacturing process for STARCEL.          840
  • Figure 151. Manufacturing process for STARCEL.          844
  • Figure 152. 3D printed cellulose shoe. 852
  • Figure 153. Lyocell process.     855
  • Figure 154. North Face Spiber Moon Parka.      859
  • Figure 155. PANGAIA LAB NXT GEN Hoodie.    860
  • Figure 156. Spider silk production.        861
  • Figure 157. Stora Enso lignin battery materials.              865
  • Figure 158. 2 wt.％ CNF suspension.   866
  • Figure 159. BiNFi-s Dry Powder.             867
  • Figure 160. BiNFi-s Dry Powder and Propylene (PP) Complex Pellet.   867
  • Figure 161. Silk nanofiber (right) and cocoon of raw material. 868
  • Figure 162. Sulapac cosmetics containers.      869
  • Figure 163.  Sulzer equipment for PLA polymerization processing.       870
  • Figure 164. Solid Novolac Type lignin modified phenolic resins.             871
  • Figure 165. Teijin bioplastic film for door handles.         880
  • Figure 166. Corbion FDCA production process.              887
  • Figure 167. Comparison of weight reduction effect using CNF.              889
  • Figure 168. CNF resin products.             893
  • Figure 169. UPM biorefinery process.  894
  • Figure 170. Vegea production process.               899
  • Figure 171. The Proesa® Process.          901
  • Figure 172. Goldilocks process and applications.         902
  • Figure 173. Visolis’ Hybrid Bio-Thermocatalytic Process.         905
  • Figure 174. HefCel-coated wood (left) and untreated wood (right) after 30 seconds flame test.            908
  • Figure 175. Worn Again products.          913
  • Figure 176. Zelfo Technology GmbH CNF production process.               917
  • Figure 177. Global revenues for biochemicals, by type (2020-2035), billions USD.       937
  • Figure 178. Global revenues for biochemicals, by applications market (2020-2035), billions USD.      938
  • Figure 179. Global revenues for biochemicals, by regional market (2020-2035), billions USD.               939
  • Figure 180. formicobio™ technology.    956
  • Figure 181. Domsjö process.    960
  • Figure 182.  TMP-Bio Process. 965
  • Figure 183. Lignin gel.  984
  • Figure 184. BioFlex process.     986
  • Figure 185. LX Process.               988
  • Figure 186. METNIN™ Lignin refining technology.           992
  • Figure 187. Enfinity cellulosic ethanol technology process.     998
  • Figure 188.  Precision Photosynthesis™ technology.    1000
  • Figure 189. Fabric consisting of 70 per cent wool and 30 per cent Qmilk.          1001
  • Figure 190. UPM biorefinery process.  1011
  • Figure 191. The Proesa® Process.          1012
  • Figure 192. Goldilocks process and applications.         1013
  • Figure 193. Global revenues for Bio Agritech products, by applications market (2020-2035), billions USD.     1037
  • Figure 194. Global revenues for Bio Agritech products, by regional market (2020-2035), billions USD.              1038

 

 

 

 

The Global Biomanufacturing Market 2024-2035
The Global Biomanufacturing Market 2024-2035
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