- Published: May 2024
- Pages: 200
- Tables: 40
- Figures: 7
Biocatalysts are increasingly being adopted due to the important role they play in helping meet the more prominent sustainability goals of the pharmaceutical, agrochemical, and fine chemical industries. Biocatalysts offer several advantages over traditional chemical catalysts including:
- High reaction specificity leading to less by-products and simpler purification
- Ability to perform challenging chemistries not feasible by conventional organic synthesis
- Mild reaction conditions like ambient temperatures and neutral pH enabling energy savings
- Reduced use of toxic reagents and solvents aligned with green chemistry principles
- Improved stereoselectivity for production of single enantiomers critical for pharmaceutical activity
- Flexible substrate scope from natural enzyme evolution
- Biodegradability and derived from renewable resources
The Global Market for Biocatalysts 2024-2035 is a comprehensive market research report that provides an in-depth analysis of the rapidly evolving biocatalysts industry. This report covers the current state and future prospects of various types of biocatalysts, including enzymes, microorganisms, and engineered biocatalysts, as well as their applications across diverse sectors such as food and beverage, pharmaceuticals, chemicals, textiles, paper and pulp, and biofuels.
- Executive summary: concise overview of the global biocatalysts market, including market size and growth projections, major players, competitive landscape, and future outlook. The introduction section provides a clear definition and classification of biocatalysts, along with a brief history of their evolution and the importance of biocatalysts in industrial processes.
- Technology overview: covering various aspects of biocatalyst technology such as biotransformations, cascade biocatalysis, co-factor recycling, and immobilization. The report also delves into the different types of biocatalysts, including enzymes, microorganisms (bacteria, fungi, yeast, and archaea), engineered biocatalysts (directed evolution, rational design, semi-rational design, immobilization, and fusion proteins), and other types such as ribozymes, DNAzymes, abzymes, nanozymes, and organocatalysts. The production methods and processes for biocatalysts, such as fermentation, recombinant DNA technology, cell-free protein synthesis, extraction from natural sources, and solid-state fermentation, are also discussed in detail.
- Emerging technologies and innovations in biocatalysis: including synthetic biology and metabolic engineering, generative biology and artificial intelligence, genome engineering, immobilization and encapsulation techniques, biomimetics, nanoparticle-based biocatalysts, biocatalytic cascades and multi-enzyme systems, and microfluidics.
- Market analysis: provides valuable insights into the market drivers, challenges, price and cost analysis, supply chain, and opportunities. The report also covers the regulatory framework and government initiatives related to biocatalysts. A comprehensive analysis of the markets and applications for biocatalysts is presented, covering sectors such as food and beverage, pharmaceutical and biotechnology, chemicals, textiles, paper and pulp, biofuels and bioenergy, and other emerging applications like cosmetics and personal care, leather processing, mining and metal extraction, environmental remediation, and waste valorization. The report includes global revenue forecasts for biocatalysts by market and region, as well as a detailed competitive landscape analysis.
Additionally, the report features 60 company profiles of key players in the biocatalysts industry, providing valuable insights into their strategies, products, and technologies. Companies profiled include Aether Bio, Basecamp Research, Cascade Biocatalysts, Constructive Bio, Debut Biotechnology, Enginzyme AB, eversyn, FabricNano, Johnson Matthey, Novozymes A/S and Protein Evolution.
1 EXECUTIVE SUMMARY 11
- 1.1 Overview of the global biocatalysts market 11
- 1.2 Market size and growth projections 12
- 1.3 Major players and competitive landscape 13
- 1.4 Future outlook 14
2 INTRODUCTION 15
- 2.1 Definition and classification of biocatalysts 15
- 2.2 History and evolution of biocatalysts 16
- 2.3 Importance of biocatalysts in industrial processes 17
3 TECHNOLOGY OVERVIEW 20
- 3.1 Overview of biocatalyst technology 20
- 3.1.1 Biotransformations 21
- 3.1.2 Cascade biocatalysis 21
- 3.1.3 Co-factor recycling 21
- 3.1.4 Immobilization 22
- 3.2 Types of biocatalysts 23
- 3.2.1 Enzymes 24
- 3.2.2 Feedstocks 26
- 3.2.3 Protein/Enzyme Engineering 27
- 3.2.4 Microorganisms 28
- 3.2.4.1 Bacteria 29
- 3.2.4.2 Fungi 29
- 3.2.4.3 Yeast 30
- 3.2.4.4 Archaea 32
- 3.2.5 Engineered biocatalysts 33
- 3.2.5.1 Directed Evolution 33
- 3.2.5.2 Rational Design 34
- 3.2.5.3 Semi-Rational Design 35
- 3.2.5.4 Immobilization 36
- 3.2.5.5 Fusion Proteins 36
- 3.2.6 Other types 38
- 3.2.6.1 Ribozymes 38
- 3.2.6.2 DNAzymes 39
- 3.2.6.3 Abzymes 40
- 3.2.6.4 Nanozymes 41
- 3.2.6.5 Organocatalysts 42
- 3.3 Production methods and processes 43
- 3.3.1 Fermentation 44
- 3.3.2 Recombinant DNA technology 47
- 3.3.3 Cell-Free Protein Synthesis 48
- 3.3.4 Extraction from Natural Sources 49
- 3.3.5 Solid-State Fermentation 50
- 3.4 Emerging technologies and innovations in biocatalysis 51
- 3.4.1 Synthetic biology and metabolic engineering 51
- 3.4.1.1 Batch biomanufacturing 57
- 3.4.1.2 Continuous biomanufacturing 58
- 3.4.1.3 Fermentation Processes 59
- 3.4.1.4 Cell-free synthesis 59
- 3.4.1 Synthetic biology and metabolic engineering 51
- 3.4.2 Generative biology and Artificial Intelligence (AI) 63
- 3.4.2.1 Molecular Dynamics Simulations 63
- 3.4.2.2 Quantum Mechanical Calculations 64
- 3.4.2.3 Systems Biology Modeling 64
- 3.4.2.4 Metabolic Engineering Modeling 65
- 3.4.3 Genome engineering 67
- 3.4.4 Immobilization and encapsulation techniques 69
- 3.4.5 Biomimetics 70
- 3.4.6 Nanoparticle-based biocatalysts 70
- 3.4.7 Biocatalytic cascades and multi-enzyme systems 73
- 3.4.8 Microfluidics 74
4 MARKET ANALYSIS 77
- 4.1 Market drivers 77
- 4.2 Market challenges 78
- 4.3 Price and cost analysis 80
- 4.4 Market supply chain 81
- 4.5 Market opportunities 82
- 4.6 Regulatory framework and government initiatives 84
- 4.7 Markets and applications 86
- 4.7.1 Food and beverage 88
- 4.7.1.1 Dairy products 89
- 4.7.1.2 Bakery and confectionery 89
- 4.7.1.3 Brewing and winemaking 90
- 4.7.1.4 Other food and beverage applications 91
- 4.7.2 Pharmaceutical and biotechnology 93
- 4.7.2.1 Drug synthesis and manufacturing 93
- 4.7.2.2 Vaccine production 94
- 4.7.2.3 Diagnostic and therapeutic enzymes 95
- 4.7.2.4 Personalized medicine and drug discovery 95
- 4.7.2.5 Other pharmaceutical and biotech applications 96
- 4.7.3 Chemicals 98
- 4.7.3.1 Polymers and plastics 98
- 4.7.3.2 Agrochemicals and fertilizers 99
- 4.7.3.3 Detergents and cleaning products 101
- 4.7.3.4 Other chemical applications 102
- 4.7.4 Textiles 104
- 4.7.4.1 Textile processing and finishing 105
- 4.7.4.2 Denim and jeans manufacturing 107
- 4.7.4.3 Other textile applications 108
- 4.7.5 Paper and pulp 110
- 4.7.5.1 Pulping and bleaching 112
- 4.7.5.2 Deinking and recycling 113
- 4.7.5.3 Other paper and pulp applications 114
- 4.7.6 Biofuels and bioenergy 114
- 4.7.6.1 Bioethanol production 115
- 4.7.6.2 Biodiesel production 115
- 4.7.6.3 Biogas and biomethane production 116
- 4.7.6.4 Metabolic Engineering for Biofuel Synthesis 117
- 4.7.7 Other emerging applications 119
- 4.7.7.1 Cosmetics and personal care 120
- 4.7.7.2 Leather processing 121
- 4.7.7.3 Mining and metal extraction 122
- 4.7.7.4 Environmental remediation and waste treatment 122
- 4.7.7.5 Waste valorization and circular economy 123
- 4.7.1 Food and beverage 88
- 4.8 Global revenues 126
- 4.8.1 By market 126
- 4.8.2 By region 128
- 4.9 Competitive Landscape 130
5 COMPANY PROFILES 133 (60 company profiles)
6 RESEARCH METHODOLOGY 191
7 LIST OF ABBREVIATIONS 192
8 GLOSSARY OF TERMS 195
9 REFERENCES 197
List of Tables
- Table 1. Comparison of types of biocatalysts. 23
- Table 2. Types of Enzyme Biocatalysts. 24
- Table 3. Common microbial hosts used for enzyme production. 25
- Table 4. Enzyme feedstocks. 26
- Table 5. Engineered proteins in industrial applications. 28
- Table 6. Types of Microorganism Biocatalysts. 28
- Table 7. Commonly used bacterial hosts. 29
- Table 8. Examples of fungal hosts. 29
- Table 9. Commonly used yeast hosts. 30
- Table 10. Types of Engineered Biocatalysts. 33
- Table 11. Production methods for biocatalysts. 43
- Table 12. Fermentation processes. 44
- Table 13. Waste-based feedstocks and biochemicals produced. 44
- Table 14. Microbial and mineral-based feedstocks and biochemicals produced. 45
- Table 15. Key biomanufacturing processes utilized in synthetic biology. 55
- Table 16. Molecules produced through industrial biomanufacturing. 56
- Table 17. Continuous vs batch biomanufacturing 57
- Table 18. Key fermentation parameters in batch vs continuous biomanufacturing processes. 57
- Table 19. Synthetic biology fermentation processes. 59
- Table 20. Cell-free versus cell-based systems 60
- Table 21. Key applications of genome engineering. 68
- Table 22. Types of Nanoparticle Biocatalysts. 70
- Table 23. Types of Biocatalytic Cascades and Multi-Enzyme Systems. 73
- Table 24. Market drivers for biocatalysts. 77
- Table 25. Market challenges in biocatalysts. 78
- Table 26. Price and Costs Analysis for biocatalysts. 80
- Table 27. Regulatory framework and government initiatives pertaining to biocatalysts. 84
- Table 28. Markets and applications for biocatalysts. 86
- Table 29. Applications of Biocatalysts in Food and Beverage. 88
- Table 30. Applications of Biocatalysts in Pharma and Biotechnology. 93
- Table 31. Applications of Biocatalysts in the Chemicals Industry. 98
- Table 32. Applications of Biocatalysts in Textiles. 104
- Table 33. Applications of Biocatalysts in Paper and Pulp. 110
- Table 34. Applications of Biocatalysts in Biofuels and Energy. 114
- Table 35. Global market size and forecast for biocatalysts, by application segment (millions USD). 126
- Table 36. Global market for biocatalysts, by region, 2020-2035 (millions USD). 128
- Table 37. Overview of the competitive landscape. 130
- Table 38. Strategic collaborations and partnerships 131
- Table 39. List of Abbreviations. 192
- Table 40. Glossary of terms. 195
List of Figures
- Figure 1. History and evolution of biocatalysts. 16
- Figure 2. Cell-free and cell-based protein synthesis systems. 62
- Figure 3. Biocatalysts Supply Chain. 81
- Figure 4. Global market size and forecast for biocatalysts, by application segment(millions USD). 127
- Figure 5. Global market for biocatalysts, by region, 2020-2035 (millions USD). 128
- Figure 6. Light Bio Bioluminescent plants. 180
- Figure 7. METNIN™ Lignin refining technology. 182
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